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Symbol
Name
ID
Usp18
ubiquitin specific peptidase 18
MGI:1344364
Phenotype annotations related to immune system
Darker colors indicate more annotations

Mouse Phenotypes
decreased leukocyte cell number
abnormal lymphocyte morphology
decreased circulating interferon-alpha level
decreased circulating interferon-beta level
decreased circulating interferon-gamma level
increased circulating interleukin-6 level
abnormal cytokine level
decreased interferon-gamma secretion
increased interleukin-6 secretion
increased susceptibility to endotoxin shock
increased susceptibility to bacterial infection
increased susceptibility to bacterial infection induced morbidity/mortality
decreased susceptibility to Coronaviridae infection
Availability Mouse Genotype
Usp18ity9/Usp18ity9
Usp18tm1Dez/Usp18tm1Dez
Usp18ity9/Usp18tm1Dez

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory